Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3993683 | 0.93 | PTPN1 (0.46) | LMNAALDH1A1PTPN1POLBMAPT | |
| SCHEMBL3997390 | 0.90 | PPARG (0.43) | LMNAALDH1A1PTPN1POLBMAPT | |
| SCHEMBL13869734 | 0.87 | FFAR1 (0.52) | LMNAALDH1A1POLBMAPTSMN1; SMN2 | |
| SCHEMBL3996241 | 0.86 | SLC6A5 (0.50) | LMNAALDH1A1POLBMAPTSMN1; SMN2 | |
| SCHEMBL3996108 | 0.85 | FFAR1 (0.53) | LMNASMN1; SMN2FFAR1FFAR4KDM4E | |
| SCHEMBL3997895 | 0.84 | PPARA (0.49) | LMNAALDH1A1PTPN1POLBMAPT | |
| SCHEMBL3997793 | 0.83 | LTA4H (0.56) | LMNAALDH1A1POLBMAPTSMN1; SMN2 | |
| SCHEMBL3997587 | 0.81 | FFAR1 (0.50) | LMNAALDH1A1POLBMAPTSMN1; SMN2 | |
| SCHEMBL3995121 | 0.80 | SLC6A5 (0.48) | LMNAALDH1A1POLBMAPTSMN1; SMN2 | |
| SCHEMBL8588987 | 0.80 | MAOB (0.57) | LMNAALDH1A1POLBMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521461-B2 | Benzoic acid derivatives as modulators of PPAR alpha and gamma | ASTRAZENECA AB (SE) | 2009-04-21 | — | — | US | disclosed |
| US-7521461-B2 | Benzoic acid derivatives as modulators of PPAR alpha and gamma | ASTRAZENECA AB (SE) | 2009-04-21 | — | — | US | disclosed |