Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | PRKCG | P05129 | 1/20 | 0.42 |
| ▸ | PRKCB | P05771 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13869738 | 0.88 | POLB (0.56) | POLBHSD17B10ALDH1A1PTGS2KMT2A | |
| SCHEMBL4003704 | 0.86 | POLB (0.55) | POLBHSD17B10ALDH1A1KDM4EPTGS2 | |
| SCHEMBL6380511 | 0.84 | PTGS2 (0.56) | POLBHSD17B10ALDH1A1KDM4EPTGS2 | |
| SCHEMBL4964440 | 0.82 | ALDH1A1 (0.50) | POLBHSD17B10ALDH1A1KDM4EPTGS2 | |
| SCHEMBL13869746 | 0.80 | EGFR (0.49) | POLBHSD17B10ALDH1A1KDM4EPTGS2 | |
| SCHEMBL10144072 | 0.79 | HSD17B10 (0.67) | POLBHSD17B10ALDH1A1KDM4EPTGS2 | |
| SCHEMBL2797516 | 0.78 | HSD17B10 (0.65) | POLBHSD17B10ALDH1A1KDM4EKMT2A | |
| SCHEMBL21505100 | 0.78 | HSD17B10 (0.65) | POLBHSD17B10ALDH1A1KDM4EKMT2A | |
| SCHEMBL8628655 | 0.78 | POLB (0.65) | POLBHSD17B10ALDH1A1KDM4EKMT2A | |
| SCHEMBL30149651 | 0.78 | HSD17B10 (0.65) | POLBHSD17B10ALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521461-B2 | Benzoic acid derivatives as modulators of PPAR alpha and gamma | ASTRAZENECA AB (SE) | 2009-04-21 | — | — | US | disclosed |
| US-7521461-B2 | Benzoic acid derivatives as modulators of PPAR alpha and gamma | ASTRAZENECA AB (SE) | 2009-04-21 | — | — | US | disclosed |