Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.46 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.46 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.46 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.46 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6380511 | 0.88 | PTGS2 (0.56) | POLBHSD17B10KMT2AHPGDALDH1A1 | |
| SCHEMBL13869741 | 0.88 | POLB (0.57) | POLBHSD17B10KMT2AALDH1A1PTGS2 | |
| SCHEMBL4964440 | 0.86 | ALDH1A1 (0.50) | POLBHSD17B10KMT2AALDH1A1NPC1 | |
| SCHEMBL28326285 | 0.86 | POLB (0.58) | POLBHSD17B10KMT2AHPGDALDH1A1 | |
| SCHEMBL13869746 | 0.81 | EGFR (0.49) | POLBHSD17B10KMT2AALDH1A1NPC1 | |
| SCHEMBL4963765 | 0.81 | POLB (0.48) | POLBHSD17B10KMT2AHPGDALDH1A1 | |
| SCHEMBL4003704 | 0.80 | POLB (0.55) | POLBHSD17B10KMT2AALDH1A1PTGS2 | |
| SCHEMBL13869757 | 0.80 | MAPK1 (0.60) | POLBHSD17B10KMT2AALDH1A1NPC1 | |
| SCHEMBL4962386 | 0.78 | TRPM8 (0.58) | HSD17B10ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10144072 | 0.78 | HSD17B10 (0.67) | POLBHSD17B10KMT2AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521461-B2 | Benzoic acid derivatives as modulators of PPAR alpha and gamma | ASTRAZENECA AB (SE) | 2009-04-21 | — | — | US | disclosed |