Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.76 |
| ▸ | NPC1 | O15118 | 5/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.68 |
| ▸ | MEN1 | O00255 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.51 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8790130 | 0.83 | RAB9A (0.81) | RAB9ANPC1SMN1; SMN2MAPK1KMT2A | |
| SCHEMBL8789867 | 0.79 | ALDH1A1 (0.77) | RAB9ANPC1SMN1; SMN2MAPK1KMT2A | |
| SCHEMBL3963799 | 0.78 | RAB9A (0.63) | RAB9ANPC1SMN1; SMN2MAPK1KMT2A | |
| SCHEMBL3960751 | 0.78 | RAB9A (0.66) | RAB9ANPC1SMN1; SMN2MAPK1KMT2A | |
| SCHEMBL13869757 | 0.78 | MAPK1 (0.60) | RAB9ANPC1SMN1; SMN2MAPK1KMT2A | |
| SCHEMBL3963795 | 0.76 | RAB9A (0.63) | RAB9ANPC1SMN1; SMN2MAPK1KMT2A | |
| SCHEMBL5034528 | 0.76 | KMT2A (0.53) | RAB9ANPC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL8652025 | 0.75 | ALOX5 (0.76) | RAB9ANPC1SMN1; SMN2MAPK1KMT2A | |
| SCHEMBL7442885 | 0.75 | KMT2A (0.77) | RAB9ANPC1SMN1; SMN2MAPK1KMT2A | |
| SCHEMBL13256444 | 0.75 | RAB9A (0.71) | RAB9ANPC1SMN1; SMN2MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521461-B2 | Benzoic acid derivatives as modulators of PPAR alpha and gamma | ASTRAZENECA AB (SE) | 2009-04-21 | — | — | US | disclosed |