Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 15/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13870758 | 0.88 | PKM (0.41) | PDE7APKM | |
| SCHEMBL13870770 | 0.86 | PKM (0.42) | PDE7APKMRAB9ASMN1; SMN2 | |
| SCHEMBL13870776 | 0.76 | HTT (0.44) | HTTRAB9ASMN1; SMN2 | |
| SCHEMBL13870783 | 0.75 | HTT (0.35) | HTTP2RX7RAB9ASMN1; SMN2 | |
| SCHEMBL21960344 | 0.74 | PDE7A (0.43) | PDE7A | |
| SCHEMBL13870778 | 0.73 | HTT (0.34) | HTTP2RX7SMN1; SMN2 | |
| SCHEMBL13870780 | 0.73 | HTT (0.36) | HTTP2RX7SMN1; SMN2 | |
| SCHEMBL13870772 | 0.71 | DRD4 (0.44) | P2RX7 | |
| SCHEMBL13870781 | 0.70 | CYP1A2 (0.47) | PKMP2RX7RAB9ASMN1; SMN2 | |
| SCHEMBL27854871 | 0.69 | HPGD (0.39) | PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7517995-B2 | Thiazolyl-dihydro-cyclopentapyrazole | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-14 | — | — | US | disclosed |
| US-20070238730-A1 | THIAZOLYL-DIHYDRO-CYCLOPENTAPYRAZOLE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070238730-A1 | THIAZOLYL-DIHYDRO-CYCLOPENTAPYRAZOLE | REN, ROR1, RORB | PDE7A 1708/4885PKM 660/4885HTT 898/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.