Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 14/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13870770 | 0.99 | PKM (0.42) | PKMPDE7AKDM4EALDH1A1POLB | |
| SCHEMBL13870773 | 0.88 | PDE7A (0.38) | PKMPDE7A | |
| SCHEMBL13870772 | 0.82 | DRD4 (0.44) | POLBKMT2A | |
| SCHEMBL13870744 | 0.78 | SMN1; SMN2 (0.39) | POLBKMT2A | |
| SCHEMBL13870748 | 0.77 | MTNR1A (0.39) | KDM4EALDH1A1POLBHPGDKMT2A | |
| SCHEMBL13870756 | 0.74 | MTNR1A (0.35) | KDM4EALDH1A1POLBHPGDKMT2A | |
| SCHEMBL13870753 | 0.74 | MTNR1A (0.35) | ALDH1A1POLBKMT2A | |
| SCHEMBL13870757 | 0.74 | MTNR1A (0.38) | KDM4EALDH1A1POLBHPGDKMT2A | |
| SCHEMBL13870766 | 0.74 | MTNR1A (0.35) | ALDH1A1POLBKMT2A | |
| SCHEMBL13870759 | 0.73 | MTNR1A (0.37) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7517995-B2 | Thiazolyl-dihydro-cyclopentapyrazole | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-14 | — | — | US | disclosed |
| US-20070238730-A1 | THIAZOLYL-DIHYDRO-CYCLOPENTAPYRAZOLE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070238730-A1 | THIAZOLYL-DIHYDRO-CYCLOPENTAPYRAZOLE | REN, ROR1, RORB | PKM 660/4885PDE7A 1708/4885KDM4E 4640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.