SCHEMBL13870944

SCHEMBL13870944

COc1cc2nc(-c3ccc(C)c(C)c3)ccc2c(OC)c1OC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KATNA1 O75449 1/20 0.44
KDM4E B2RXH2 2/20 0.44
MAPT P10636 2/20 0.44
NPC1 O15118 2/20 0.43
ALDH1A1 P00352 2/20 0.43
RAB9A P51151 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
MAOA P21397 2/20 0.42
GAA P10253 1/20 0.41
ALOX15 P16050 1/20 0.41
HSD17B10 Q99714 1/20 0.41
PDGFRB P09619 2/20 0.41
PDGFRA P16234 2/20 0.41
BRD4 O60885 1/20 0.41
SLC10A2 Q12908 1/20 0.41
PDE3B Q13370 1/20 0.39
PDE3A Q14432 1/20 0.39
SLC2A1 P11166 1/20 0.39
TUBB1 Q9H4B7 1/20 0.39
TP53 P04637 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13870932 0.83 MAOA (0.44) KDM4EMAPTNPC1ALDH1A1RAB9A
SCHEMBL1337819 0.83 KDM4E (0.54) KDM4EMAPTNPC1ALDH1A1RAB9A
SCHEMBL16487820 0.83 NPC1 (0.39) KATNA1KDM4EMAPTNPC1ALDH1A1
SCHEMBL1337875 0.82 PDGFRB (0.51) KDM4EMAPTNPC1ALDH1A1RAB9A
SCHEMBL13870933 0.82 ALDH1A1 (0.48) KDM4EMAPTNPC1ALDH1A1RAB9A
SCHEMBL13870947 0.82 PSMB5 (0.44) KATNA1KDM4ENPC1ALDH1A1SMN1; SMN2
SCHEMBL13870939 0.81 KDM4E (0.55) KDM4EMAPTNPC1ALDH1A1RAB9A
SCHEMBL13870928 0.81 KDM4E (0.53) KDM4EMAPTNPC1ALDH1A1RAB9A
SCHEMBL13870941 0.80 SMN1; SMN2 (0.52) KDM4EMAPTNPC1ALDH1A1RAB9A
SCHEMBL16488129 0.80 PSMB5 (0.43) KDM4EMAPTALDH1A1MAOAPDGFRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8956737-B2 Red phosphorescent compound and organic electroluminescent device using the same LG DISPLAY CO., LTD. (KR) 2015-02-17 US disclosed
US-8956737-B2 Red phosphorescent compound and organic electroluminescent device using the same LG DISPLAY CO., LTD. (KR) 2015-02-17 US disclosed
US-20090085476-A1 RED PHOSPHORESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME LG DISPLAY CO., LTD. (KR) 2009-04-02 US disclosed
US-20090085476-A1 RED PHOSPHORESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME LG DISPLAY CO., LTD. (KR) 2009-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090085476-A1 RED PHOSPHORESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME IK, G6PD, EYA2 KATNA1 1747/4885KDM4E 2874/4885MAPT 1550/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.