SCHEMBL13871817

SCHEMBL13871817

Cc1cc(-c2nc3cccnc3n2-c2ccccc2C)c(C)cc1-c1nc2cccnc2n1-c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 14/20 0.51
AKT2 P31751 5/20 0.51
AKT3 Q9Y243 3/20 0.47
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
POLB P06746 1/20 0.41
PABPC1 P11940 1/20 0.41
TP53 P04637 1/20 0.40
MAPT P10636 1/20 0.40
PDE4B Q07343 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL804796 0.94 AKT1 (0.47) AKT1AKT2AKT3MEN1KMT2A
SCHEMBL804813 0.92 AKT1 (0.58) AKT1AKT2AKT3MEN1KMT2A
SCHEMBL13943550 0.88 TSHR (0.52) AKT1AKT2AKT3MEN1KMT2A
SCHEMBL13052968 0.87 AKT1 (0.48) AKT1AKT2AKT3MEN1KMT2A
SCHEMBL13943559 0.86 RECQL (0.52) AKT1AKT2AKT3
SCHEMBL12854007 0.84 AKT1 (0.51) AKT1AKT2AKT3MEN1KMT2A
SCHEMBL13053163 0.84 AKT1 (0.50) AKT1AKT2AKT3MEN1KMT2A
SCHEMBL12661336 0.83 MEN1 (0.50) AKT1AKT2AKT3MEN1KMT2A
SCHEMBL16139466 0.82 ALDH1A1 (0.46) AKT1AKT2AKT3MEN1KMT2A
SCHEMBL13052969 0.82 AKT1 (0.59) AKT1AKT2AKT3MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090085469-A1 LUMINESCENT METAL COMPLEX, METHOD FOR PRODUCING SAME AND ORGANIC ELECTROLUMINESCENT LIGHT-EMITTING DEVICE USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2009-04-02 US disclosed
US-20090085469-A1 LUMINESCENT METAL COMPLEX, METHOD FOR PRODUCING SAME AND ORGANIC ELECTROLUMINESCENT LIGHT-EMITTING DEVICE USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2009-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090085469-A1 LUMINESCENT METAL COMPLEX, METHOD FOR PRODUCING SAME AND ORGANIC ELECTROLUMINESCENT LIGHT-EMITTING DEVICE USING SAME EMC2, SOD1, ICOSLG AKT1 4410/4885AKT2 4739/4885AKT3 4813/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.