SCHEMBL804796

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13871817	0.94	AKT1 (0.51)	AKT1AKT2AKT3PDE4BTP53
	SCHEMBL13943550	0.94	TSHR (0.52)	AKT1AKT2TSHRAKT3PDE4B
	SCHEMBL13052968	0.93	AKT1 (0.48)	AKT1AKT2TSHRAKT3PDE4B
	SCHEMBL12854007	0.90	AKT1 (0.51)	AKT1AKT2TSHRAKT3PDE4B
	SCHEMBL14679569	0.87	AKT1 (0.38)	AKT1AKT2TSHRAKT3PDE4B
	SCHEMBL64513	0.87	TSHR (0.45)	AKT1AKT2TSHRPDE4BPDE4D
	SCHEMBL19719407	0.87	AKT1 (0.43)	AKT1AKT2TSHRAKT3PDE4B
	SCHEMBL13052947	0.86	AKT1 (0.49)	AKT1AKT2TSHRAKT3PDE4B
	SCHEMBL13052976	0.85	TSHR (0.46)	AKT1AKT2TSHRAKT3PDE4B
	SCHEMBL804993	0.85	TSHR (0.46)	AKT1AKT2TSHRAKT3PDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 179 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.