Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.35 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.35 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.30 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13872303 | 0.88 | MAP3K5 (0.43) | MAP3K5 | |
| SCHEMBL13113755 | 0.87 | MCHR1 (0.48) | MCHR1CLK4DYRK1BTYRO3NTRK2 | |
| SCHEMBL13872274 | 0.78 | MEN1 (0.32) | KMT2A | |
| SCHEMBL13872273 | 0.75 | METAP1 (0.35) | KMT2A | |
| SCHEMBL13871899 | 0.75 | MCHR1 (0.37) | MCHR1CLK4DYRK1BTYRO3NTRK2 | |
| SCHEMBL18000158 | 0.75 | HSD11B1 (0.46) | KMT2AHSD11B1 | |
| SCHEMBL13871869 | 0.74 | HTR2C (0.34) | KMT2A | |
| SCHEMBL13871937 | 0.72 | MEN1 (0.36) | KMT2A | |
| SCHEMBL13871905 | 0.72 | MEN1 (0.39) | KMT2A | |
| SCHEMBL14818556 | 0.72 | HTR1A (0.32) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009042907-A1 | ISOINDOLINE COMPOUNDS FOR THE TREATMENT OF SPINAL MUSCULAR ATROPHY AND OTHER USES | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2009-04-02 | — | — | WO | disclosed |