Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.37 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL719639 | 0.88 | LCK (0.38) | ALDH1A1THRBRECQLGABRR1CYP1A2 | |
| SCHEMBL11363406 | 0.83 | GABRR1 (0.40) | ALDH1A1GABRR1CYP1A2TP53CHRM1 | |
| SCHEMBL28610519 | 0.83 | GABRR1 (0.40) | ALDH1A1GABRR1CYP1A2TP53CHRM1 | |
| SCHEMBL11365409 | 0.83 | GABRR1 (0.40) | ALDH1A1GABRR1CYP1A2TP53CHRM1 | |
| Lactic Acid SCHEMBL27702915 | 0.81 | TP53 (0.61) | GABRR1CYP1A2TP53CHRM1AKR1A1 | |
| Ethylene Glycol SCHEMBL721630 | 0.80 | ALDH1A1 (0.44) | ALDH1A1THRBRECQLGABRR1CYP1A2 | |
| Ethylene Glycol SCHEMBL719575 | 0.80 | ALDH1A1 (0.44) | ALDH1A1THRBRECQLGABRR1CYP1A2 | |
| SCHEMBL233694 | 0.80 | — | — | |
| SCHEMBL233072 | 0.80 | — | — | |
| SCHEMBL51944 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8883941-B2 | Methods and apparatus for controlled single electron transfer living radical polymerization | HENKEL CORPORATION (US) | 2014-11-11 | — | — | US | claimed |
| US-20140275448-A1 | METHODS AND APPARATUS FOR CONTROLLED SINGLE ELECTRON TRANSFER LIVING RADICAL POLYMERIZATION | HENKEL CORPORATION (US) | 2014-09-18 | — | — | US | claimed |
| US-11814533-B2 | Curable polymeric coatings for functional surface preparations | CORNELL UNIVERSITY (US) | 2023-11-14 | — | — | US | disclosed |
| US-11008414-B2 | Polymer materials for contact lens applications | CIS PHARMA AG (CH) | 2021-05-18 | — | — | US | disclosed |
| US-20200283560-A1 | New polymer materials for contact lens applications | CIS PHARMA AG (CH) | 2020-09-10 | — | — | US | disclosed |
| US-20200216708-A1 | CURABLE POLYMERIC COATINGS FOR FUNCTIONAL SURFACE PREPARATIONS | CORNELL UNIVERSITY | 2020-07-09 | — | — | US | disclosed |
| EP-2596062-B1 | SET-LRP POLYMERIZATION OF ACRYLATES IN THE PRESENCE OF ACIDS | ROHM & HAAS (US) | 2019-09-18 | — | — | EP | disclosed |
| US-10273314-B2 | Set-LRP polymerization of acrylates in the presence of acids | ROHM AND HAAS COMPANY (US) | 2019-04-30 | — | — | US | disclosed |
| US-9243083-B2 | Thiol-ene cured oil-resistant polyacrylate sealants for in-place gasketing applications | Henkel IP & Holding GmbH (DE) | 2016-01-26 | — | — | US | disclosed |
| US-8883941-B2 | Methods and apparatus for controlled single electron transfer living radical polymerization | HENKEL CORPORATION (US) | 2014-11-11 | — | — | US | disclosed |
| US-20140275448-A1 | METHODS AND APPARATUS FOR CONTROLLED SINGLE ELECTRON TRANSFER LIVING RADICAL POLYMERIZATION | HENKEL CORPORATION (US) | 2014-09-18 | — | — | US | disclosed |
| US-20140216649-A1 | THIOL-ENE CURED OIL-RESISTANT POLYACRYLATE SEALANTS FOR IN-PLACE GASKETING APPLICATIONS | LOCTITE (R&D) LIMITED | 2014-08-07 | — | — | US | disclosed |
| US-20130245216-A1 | SET-LRP POLYMERIZATION OF ACRYLATES IN THE PRESENCE OF ACIDS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2013-09-19 | — | — | US | disclosed |
| EP-2596062-A1 | SET-LRP POLYMERIZATION OF ACRYLATES IN THE PRESENCE OF ACIDS | Rohm and Haas Company (US) | 2013-05-29 | — | — | EP | disclosed |
| US-20120226000-A1 | POLYVINYL CHLORIDE CONTAINING MULTIARMED STAR COPOLYMERS | Tekni-Plex ,Inc. (US) | 2012-09-06 | — | — | US | disclosed |
| US-20120059173-A1 | DENDRITIC MOLECULES | THE UNIVERSITY OF QUEENSLAND (AU) | 2012-03-08 | — | — | US | disclosed |
| WO-2012012705-A1 | SET-LRP POLYMERIZATION OF ACRYLATES IN THE PRESENCE OF ACIDS | ROHM AND HAAS COMPANY (US) | 2012-01-26 | — | — | WO | disclosed |
| WO-2010065809-A1 | POLYVINYL CHLORIDE CONTAINING MULTIARMED STAR COPOLYMERS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2010-06-10 | — | — | WO | disclosed |
| EP-2147042-A1 | DENDRITIC MOLECULES | The University Of Queensland (AU) | 2010-01-27 | — | — | EP | disclosed |
| WO-2008141357-A1 | DENDRITIC MOLECULES | THE UNIVERSITY OF QUEENSLAND (AU) | 2008-11-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120059173-A1 | DENDRITIC MOLECULES | CD40LG, CD40, TLR3 | ALDH1A1 3696/4885THRB 4052/4885RECQL 4264/4885 |
| US-20200283560-A1 | New polymer materials for contact lens applications | CRYAA, CRYAB, BCAT1 | ALDH1A1 4406/4885THRB 2348/4885RECQL 2269/4885 |
| US-11008414-B2 | Polymer materials for contact lens applications | CRYAA, BCAT1, CRYAB | ALDH1A1 4262/4885THRB 2290/4885RECQL 2016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.