Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CCR5 | P51681 | 10/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16862315 | 0.85 | CYP2D6 (0.43) | MEN1KMT2ACCR5TSHRALDH1A1 | |
| SCHEMBL3959286 | 0.81 | CCR5 (0.43) | MMP1MMP9MMP13ADAM17MEN1 | |
| SCHEMBL3960811 | 0.81 | CCR5 (0.43) | MMP1MMP9MMP13ADAM17MEN1 | |
| SCHEMBL13873258 | 0.81 | CCR5 (0.43) | MMP1MMP9MMP13ADAM17MEN1 | |
| SCHEMBL13873262 | 0.78 | MEN1 (0.48) | MMP1MMP9MMP13ADAM17MEN1 | |
| SCHEMBL13908440 | 0.74 | ALDH1A1 (0.41) | MEN1KMT2ACCR5TSHRALDH1A1 | |
| SCHEMBL2453256 | 0.70 | CCR5 (0.52) | MEN1KMT2ACCR5TSHRALDH1A1 | |
| SCHEMBL13873260 | 0.70 | TSHR (0.51) | MMP1MMP9MMP13ADAM17MEN1 | |
| SCHEMBL13617695 | 0.70 | CCR5 (0.43) | MEN1KMT2ACCR5TSHRALDH1A1 | |
| SCHEMBL6553757 | 0.69 | MEN1 (0.43) | MMP1MMP9MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090093501-A1 | Heterocyclic antiviral compounds | ROCHE PALO ALTO LLC | 2009-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090093501-A1 | Heterocyclic antiviral compounds | CCR5, CCR1, CCR2 | MMP1 3519/4885MMP9 3524/4885MMP13 3582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.