Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | TPMT | P51580 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13875415 | 0.87 | MAPT (0.41) | MAPTPOLBSMN1; SMN2TSHRCYP1A2 | |
| SCHEMBL13875437 | 0.85 | CES2 (0.41) | MAPTSMN1; SMN2CA1CA2KMT2A | |
| SCHEMBL13875414 | 0.84 | TSHR (0.44) | MAPTPOLBSMN1; SMN2TSHRCYP1A2 | |
| SCHEMBL14845460 | 0.81 | THRB (0.30) | — | |
| SCHEMBL14845436 | 0.81 | THRB (0.33) | TSHRALDH1A1 | |
| SCHEMBL13875386 | 0.80 | THRB (0.43) | MAPTPOLBSMN1; SMN2TSHRMAPK1 | |
| SCHEMBL13875441 | 0.80 | KDM4E (0.32) | MAPTPOLBKDM4EALDH1A1LMNA | |
| SCHEMBL13875424 | 0.80 | RAB9A (0.37) | MAPTSMN1; SMN2TSHRMAPK1KDM4E | |
| SCHEMBL14845445 | 0.79 | THRB (0.32) | — | |
| SCHEMBL13875434 | 0.77 | CES2 (0.46) | MAPTSMN1; SMN2CYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090092768-A1 | Process for the Production of Strongly Adherent Coatings | CIBA SPECIALTY CHEMICALS CORP. | 2009-04-09 | — | — | US | disclosed |