Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13875434 | 0.92 | CES2 (0.46) | MAPTCES2CES1NPC1RAB9A | |
| SCHEMBL13875394 | 0.87 | MAPT (0.42) | MAPTCES2CES1POLBAPEX1 | |
| SCHEMBL13875437 | 0.86 | CES2 (0.41) | MAPTCES2CES1NPC1RAB9A | |
| SCHEMBL14845444 | 0.86 | THRB (0.35) | MAPTPOLBAPEX1HTTTDP1 | |
| SCHEMBL13875415 | 0.85 | MAPT (0.41) | MAPTCES2CES1POLBCYP1A2 | |
| SCHEMBL14845473 | 0.85 | THRB (0.34) | MAPTPOLBAPEX1HTTTDP1 | |
| SCHEMBL13875443 | 0.85 | POLB (0.34) | MAPTPOLBAPEX1HTTTDP1 | |
| SCHEMBL13875425 | 0.85 | RAB9A (0.37) | MAPTPOLBAPEX1HTTTDP1 | |
| SCHEMBL13875433 | 0.83 | CES2 (0.47) | MAPTCES2CES1NPC1RAB9A | |
| SCHEMBL14845472 | 0.81 | POLB (0.33) | POLBAPEX1HTTTDP1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090092768-A1 | Process for the Production of Strongly Adherent Coatings | CIBA SPECIALTY CHEMICALS CORP. | 2009-04-09 | — | — | US | disclosed |