Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14845460 | 0.86 | THRB (0.30) | THRB | |
| SCHEMBL14845444 | 0.85 | THRB (0.35) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL14845438 | 0.84 | PKM (0.33) | PKM | |
| SCHEMBL13875415 | 0.83 | MAPT (0.41) | POLB | |
| SCHEMBL13875394 | 0.82 | MAPT (0.42) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL13875436 | 0.81 | MAPT (0.49) | POLBAPEX1HTTTDP1PKM | |
| SCHEMBL14845473 | 0.80 | THRB (0.34) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL13875425 | 0.80 | RAB9A (0.37) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL13875443 | 0.80 | POLB (0.34) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL13875434 | 0.72 | CES2 (0.46) | PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8414982-B2 | Process for the production of strongly adherent coatings | BASF SE (DE) | 2013-04-09 | — | — | US | disclosed |