Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 9/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | HTR1E | P28566 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13875849 | 0.86 | DPP4 (0.39) | DPP4POLBSIRT5TLR7CHRNB2 | |
| SCHEMBL13875671 | 0.82 | DPP4 (0.38) | MAPTDPP4POLBALDH1A1SIRT5 | |
| SCHEMBL13876102 | 0.80 | DPP4 (0.53) | MAPTMAPK1DPP4POLBALDH1A1 | |
| SCHEMBL13875846 | 0.79 | TLR7 (0.41) | DPP4POLBALDH1A1SIRT5TLR7 | |
| SCHEMBL13875685 | 0.78 | TLR7 (0.40) | TLR7TLR8 | |
| SCHEMBL13876297 | 0.76 | DPP4 (0.45) | MAPK1DPP4POLBALDH1A1SIRT5 | |
| SCHEMBL13876124 | 0.76 | HTR3A (0.37) | MAPTALDH1A1TLR7GAATLR8 | |
| SCHEMBL13875841 | 0.75 | DPP4 (0.38) | DPP4POLBALDH1A1SIRT5TLR7 | |
| SCHEMBL13875751 | 0.74 | HRH4 (0.51) | DPP4POLBALDH1A1SIRT5CHRNB2 | |
| SCHEMBL13866874 | 0.74 | DPP4 (0.42) | DPP4POLBALDH1A1SIRT5CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524847-B2 | Fused 1,3-dihydro-imidazole ring compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |