Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 12/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13875685 | 0.89 | TLR7 (0.40) | HTR3ATLR7TLR8 | |
| SCHEMBL13875682 | 0.86 | TLR7 (0.39) | TLR7TLR8 | |
| SCHEMBL13876308 | 0.84 | TLR7 (0.42) | TLR7TLR8 | |
| SCHEMBL13875864 | 0.82 | TLR7 (0.49) | TLR7TLR8 | |
| SCHEMBL13875671 | 0.80 | DPP4 (0.38) | ALDH1A1GAAMAPT | |
| SCHEMBL13875885 | 0.76 | SLC2A1 (0.42) | HTR3AALDH1A1GAA | |
| SCHEMBL13875672 | 0.76 | MAPT (0.38) | ALDH1A1GAATLR7MAPTTLR8 | |
| SCHEMBL13866918 | 0.74 | DPP4 (0.44) | HTR3AMAPT | |
| SCHEMBL10244864 | 0.74 | DPP4 (0.49) | — | |
| SCHEMBL13875683 | 0.73 | SLC2A1 (0.53) | HTR3AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524847-B2 | Fused 1,3-dihydro-imidazole ring compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |