Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 18/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13876124 | 0.89 | HTR3A (0.37) | TLR7TLR8HTR3A | |
| SCHEMBL13875849 | 0.82 | DPP4 (0.39) | TLR7TLR8 | |
| SCHEMBL13875672 | 0.78 | MAPT (0.38) | TLR7TLR8 | |
| SCHEMBL13875682 | 0.78 | TLR7 (0.39) | TLR7TLR8 | |
| SCHEMBL13876308 | 0.76 | TLR7 (0.42) | TLR7TLR8 | |
| SCHEMBL13866946 | 0.75 | DPP4 (0.43) | HTR3A | |
| SCHEMBL13875864 | 0.72 | TLR7 (0.49) | TLR7TLR8 | |
| Trifluoroacetic Acid SCHEMBL3875625 | 0.70 | DPP4 (0.38) | — | |
| SCHEMBL13876102 | 0.69 | DPP4 (0.53) | TLR7 | |
| SCHEMBL13876141 | 0.69 | DPP4 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524847-B2 | Fused 1,3-dihydro-imidazole ring compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |