Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | EDNRA | P25101 | 1/20 | 0.37 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 3/20 | 0.35 |
| ▸ | DPP4 | P27487 | 4/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13876123 | 0.90 | P2RX3 (0.42) | P2RX3LMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL13866884 | 0.86 | DPP4 (0.45) | P2RX3DPP4 | |
| SCHEMBL13876140 | 0.83 | DPP4 (0.52) | P2RX3DPP4PIM1 | |
| SCHEMBL13875834 | 0.82 | DPP4 (0.46) | LMNACYP2C9HTR2CDPP4PIM1 | |
| SCHEMBL13875679 | 0.82 | DPP4 (0.35) | P2RX3LMNACYP2C9HTR2CDPP4 | |
| Trifluoroacetic Acid SCHEMBL3877608 | 0.82 | DPP4 (0.41) | P2RX3DPP4 | |
| SCHEMBL13876136 | 0.81 | DPP4 (0.48) | P2RX3LMNACYP2C9HTR2CDPP4 | |
| Trifluoroacetic Acid SCHEMBL5760849 | 0.80 | LMNA (0.35) | P2RX3LMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL13875681 | 0.78 | DPP4 (0.42) | P2RX3HTR2CDPP4PIM1ALDH1A1 | |
| SCHEMBL13866888 | 0.77 | DPP4 (0.45) | P2RX3DPP4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524847-B2 | Fused 1,3-dihydro-imidazole ring compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |