Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.35 |
| ▸ | HTR2C | P28335 | 3/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | CASP1 | P29466 | 3/20 | 0.33 |
| ▸ | CASP7 | P55210 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13866885 | 0.88 | DPP4 (0.47) | DPP4P2RX3 | |
| SCHEMBL13875834 | 0.82 | DPP4 (0.46) | DPP4HTR2CPIM1ALDH1A1CYP2C9 | |
| SCHEMBL13875677 | 0.82 | P2RX3 (0.43) | DPP4HTR2CP2RX3PIM1ALDH1A1 | |
| SCHEMBL13876123 | 0.81 | P2RX3 (0.42) | DPP4HTR2CP2RX3PIM1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL3883168 | 0.81 | DPP4 (0.41) | DPP4P2RX3ALDH1A1 | |
| SCHEMBL13876136 | 0.81 | DPP4 (0.48) | DPP4HTR2CP2RX3ALDH1A1HPGD | |
| SCHEMBL13876140 | 0.81 | DPP4 (0.52) | DPP4P2RX3PIM1ADORA2AADORA2B | |
| SCHEMBL13875678 | 0.79 | P2RX3 (0.40) | DPP4HTR2CP2RX3ALDH1A1HPGD | |
| SCHEMBL13866892 | 0.79 | DPP4 (0.47) | DPP4ALDH1A1HPGDCYP1A2CASP1 | |
| SCHEMBL13866882 | 0.78 | DPP4 (0.50) | DPP4P2RX3PIM1ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524847-B2 | Fused 1,3-dihydro-imidazole ring compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |