Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.53 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.53 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.42 |
| ▸ | USP2 | O75604 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.42 |
| ▸ | CASP1 | P29466 | 5/20 | 0.42 |
| ▸ | CASP7 | P55210 | 5/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13876148 | 0.89 | CHRNB2 (0.43) | SLC2A1SLC2A3NPY5RCYP1A2USP2 | |
| SCHEMBL13875885 | 0.86 | SLC2A1 (0.42) | SLC2A1SLC2A3NPY5RCYP1A2USP2 | |
| SCHEMBL13875865 | 0.83 | SLC2A1 (0.45) | SLC2A1SLC2A3NPY5RCYP1A2USP2 | |
| SCHEMBL13875671 | 0.80 | DPP4 (0.38) | SLC2A1SLC2A3NPY5RCYP1A2USP2 | |
| SCHEMBL13875868 | 0.78 | CYP1A2 (0.48) | SLC2A1SLC2A3CYP1A2USP2ALDH1A1 | |
| SCHEMBL13876307 | 0.78 | SLC2A1 (0.66) | SLC2A1SLC2A3CYP1A2USP2ALDH1A1 | |
| SCHEMBL13875682 | 0.77 | TLR7 (0.39) | — | |
| SCHEMBL13876297 | 0.76 | DPP4 (0.45) | NPY5RCYP1A2USP2ALDH1A1CYP3A4 | |
| SCHEMBL13876308 | 0.75 | TLR7 (0.42) | — | |
| SCHEMBL10244864 | 0.74 | DPP4 (0.49) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524847-B2 | Fused 1,3-dihydro-imidazole ring compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |