Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 10/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.48 |
| ▸ | CASP1 | P29466 | 8/20 | 0.48 |
| ▸ | CASP7 | P55210 | 8/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 8/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
| ▸ | HTR3B | O95264 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 7/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13875865 | 0.85 | SLC2A1 (0.45) | CYP1A2ALDH1A1CASP1CASP7HSD17B10 | |
| SCHEMBL13876126 | 0.84 | CSNK2A1 (0.41) | CYP1A2ALDH1A1CASP1CASP7HSD17B10 | |
| SCHEMBL13875754 | 0.81 | HTR2C (0.39) | CYP1A2CYP2C9CYP3A4HTR3EHTR3B | |
| SCHEMBL13876137 | 0.80 | CYP1A2 (0.36) | CYP1A2ALDH1A1HSD17B10CYP2C9USP2 | |
| SCHEMBL13875756 | 0.79 | CHRNB2 (0.45) | CYP1A2ALDH1A1CYP2C9CYP3A4HTR3E | |
| SCHEMBL13875683 | 0.78 | SLC2A1 (0.53) | CYP1A2ALDH1A1CASP1CASP7HSD17B10 | |
| SCHEMBL13875885 | 0.76 | SLC2A1 (0.42) | CYP1A2ALDH1A1CASP1CASP7HSD17B10 | |
| SCHEMBL13866874 | 0.75 | DPP4 (0.42) | CYP1A2ALDH1A1CASP1CASP7HSD17B10 | |
| SCHEMBL13866907 | 0.74 | CYP1A2 (0.42) | CYP1A2ALDH1A1CASP1CASP7HSD17B10 | |
| SCHEMBL13876148 | 0.72 | CHRNB2 (0.43) | CYP1A2ALDH1A1CASP1CASP7HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524847-B2 | Fused 1,3-dihydro-imidazole ring compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |