Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 16/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13875682 | 0.91 | TLR7 (0.39) | TLR7TLR8 | |
| SCHEMBL13875864 | 0.84 | TLR7 (0.49) | TLR7TLR8 | |
| SCHEMBL13876124 | 0.84 | HTR3A (0.37) | TLR7TLR8 | |
| SCHEMBL13875671 | 0.84 | DPP4 (0.38) | — | |
| SCHEMBL13876117 | 0.83 | ADORA1 (0.41) | TLR7ADORA1ADORA2AADORA2B | |
| SCHEMBL13875849 | 0.76 | DPP4 (0.39) | TLR7TLR8 | |
| SCHEMBL10244864 | 0.76 | DPP4 (0.49) | — | |
| SCHEMBL13875685 | 0.76 | TLR7 (0.40) | TLR7TLR8 | |
| SCHEMBL13875683 | 0.75 | SLC2A1 (0.53) | — | |
| SCHEMBL13866924 | 0.74 | DPP4 (0.48) | ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524847-B2 | Fused 1,3-dihydro-imidazole ring compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |