Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.38 |
| ▸ | PDE4A | P27815 | 2/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13866993 | 0.86 | DPP4 (0.44) | HTR2CADORA2BTLR7ADORA2APDE4A | |
| SCHEMBL13875892 | 0.85 | HTR2C (0.44) | HTR2CADORA2BTLR7ADORA2APDE4A | |
| SCHEMBL13875889 | 0.82 | HTR2C (0.43) | HTR2CADORA2BTLR7ALDH1A1ENPP1 | |
| SCHEMBL13875776 | 0.81 | HTR2C (0.42) | HTR2CTLR7PDE4APDE4BPDE4C | |
| Trifluoroacetic Acid SCHEMBL3873547 | 0.79 | DPP4 (0.38) | HTR2CADORA2B | |
| SCHEMBL13876133 | 0.74 | DPP4 (0.57) | KMT2ACYP3A4LMNA | |
| SCHEMBL13867003 | 0.73 | DPP4 (0.44) | HTR2C | |
| SCHEMBL13867030 | 0.73 | DPP4 (0.57) | HTR2CTLR7 | |
| SCHEMBL13875903 | 0.72 | HTR2C (0.50) | HTR2CTLR7ALDH1A1HTT | |
| SCHEMBL13876313 | 0.72 | HTR2C (0.38) | HTR2CTLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524847-B2 | Fused 1,3-dihydro-imidazole ring compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |