Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.35 |
| ▸ | HTR6 | P50406 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13866972 | 0.88 | DPP4 (0.40) | HTR2CPRKCAPRKCDPRKD1 | |
| Trifluoroacetic Acid SCHEMBL3879283 | 0.82 | DPP4 (0.38) | HRH4 | |
| SCHEMBL13875892 | 0.73 | HTR2C (0.44) | HTR2CTLR7KDM4ENPC1MAPK1 | |
| SCHEMBL13875686 | 0.72 | HTR2C (0.43) | HTR2CTLR7 | |
| SCHEMBL13875889 | 0.72 | HTR2C (0.43) | HTR2CTLR7KDM4ENPC1 | |
| SCHEMBL13866963 | 0.71 | DPP4 (0.48) | KDM4ENPC1RAB9A | |
| SCHEMBL13875776 | 0.71 | HTR2C (0.42) | HTR2CTLR7 | |
| SCHEMBL13866966 | 0.70 | DPP4 (0.41) | HTR2C | |
| SCHEMBL13866961 | 0.70 | DPP4 (0.41) | KDM4E | |
| SCHEMBL1432978 | 0.69 | ADRB2 (0.56) | HTR2CHRH4HTR6HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524847-B2 | Fused 1,3-dihydro-imidazole ring compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |