Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13866997 | 0.88 | DPP4 (0.45) | HTR2CTLR7ADORA2BGLABLM | |
| SCHEMBL13875892 | 0.83 | HTR2C (0.44) | HTR2CTLR7ADORA2BALDH1A1ENPP1 | |
| SCHEMBL13875686 | 0.82 | HTR2C (0.43) | HTR2CTLR7ADORA2BALDH1A1ENPP1 | |
| SCHEMBL13875776 | 0.81 | HTR2C (0.42) | HTR2CTLR7ALDH1A1ABCC1ENPP1 | |
| Trifluoroacetic Acid SCHEMBL3874210 | 0.81 | DPP4 (0.39) | HTR2CADORA2BDPP4 | |
| SCHEMBL13876133 | 0.77 | DPP4 (0.57) | DPP4KDM4E | |
| SCHEMBL13867003 | 0.75 | DPP4 (0.44) | HTR2CDPP4 | |
| SCHEMBL13867026 | 0.74 | DPP4 (0.56) | HTR2CTLR7DPP4 | |
| SCHEMBL13866993 | 0.73 | DPP4 (0.44) | HTR2CTLR7ADORA2BDPP4 | |
| SCHEMBL13867010 | 0.73 | DPP4 (0.53) | ALDH1A1ABCC1DPP4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524847-B2 | Fused 1,3-dihydro-imidazole ring compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |