Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.32 |
| ▸ | HTR3B | O95264 | 2/20 | 0.32 |
| ▸ | HTR3A | P46098 | 2/20 | 0.32 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.32 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | HTR6 | P50406 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13875865 | 0.85 | SLC2A1 (0.45) | HTR2CPRKCQSLC2A1SLC2A3DPP4 | |
| SCHEMBL13876126 | 0.81 | CSNK2A1 (0.41) | HTR2CPRKCQSLC2A1SLC2A3LMNA | |
| SCHEMBL13876137 | 0.81 | CYP1A2 (0.36) | HTR2CPRKCQSLC2A1SLC2A3ADRB1 | |
| SCHEMBL13875868 | 0.81 | CYP1A2 (0.48) | SLC2A1SLC2A3ADRB1HTR3EHTR3B | |
| SCHEMBL13875756 | 0.81 | CHRNB2 (0.45) | HTR2CCHEK1PRKCQSLC2A1SLC2A3 | |
| SCHEMBL13866874 | 0.74 | DPP4 (0.42) | HTR2CDPP4POLBSIRT5LMNA | |
| SCHEMBL13866910 | 0.72 | DPP4 (0.45) | DPP4CHRM1 | |
| SCHEMBL13876117 | 0.70 | ADORA1 (0.41) | HTR2CDPP4SIRT5 | |
| SCHEMBL13876116 | 0.69 | TLR7 (0.42) | DPP4HTR6KMT2ACYP3A4 | |
| SCHEMBL13875683 | 0.69 | SLC2A1 (0.53) | SLC2A1SLC2A3ADRB1HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524847-B2 | Fused 1,3-dihydro-imidazole ring compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |