Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 4/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.31 |
| ▸ | HTR6 | P50406 | 2/20 | 0.31 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.31 |
| ▸ | HTR3B | O95264 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13875865 | 0.84 | SLC2A1 (0.45) | CYP1A2CYP3A4LMNAMAPTHTR2C | |
| SCHEMBL13876154 | 0.82 | SLC2A1 (0.48) | CYP1A2CYP3A4LMNAMAPTHTR2C | |
| SCHEMBL13875754 | 0.81 | HTR2C (0.39) | CYP1A2CYP3A4LMNAHTR2CCYP2D6 | |
| SCHEMBL13876126 | 0.80 | CSNK2A1 (0.41) | CYP1A2CYP3A4LMNAHTR2CUSP2 | |
| SCHEMBL13875756 | 0.80 | CHRNB2 (0.45) | CYP1A2CYP3A4HTR2CCYP2D6ALDH1A1 | |
| SCHEMBL13875868 | 0.80 | CYP1A2 (0.48) | CYP1A2CYP3A4LMNAMAPTUSP2 | |
| SCHEMBL13866874 | 0.74 | DPP4 (0.42) | CYP1A2CYP3A4LMNAHTR2CUSP2 | |
| SCHEMBL13866909 | 0.73 | DPP4 (0.42) | CHRM1 | |
| SCHEMBL12067367 | 0.70 | CCNC (0.41) | CYP1A2ALDH1A1HSD17B10CLK4CHRM2 | |
| SCHEMBL13876117 | 0.69 | ADORA1 (0.41) | HTR2CHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524847-B2 | Fused 1,3-dihydro-imidazole ring compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |