Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.42 |
| ▸ | CKS1B | P61024 | 2/20 | 0.41 |
| ▸ | SKP1 | P63208 | 2/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 2/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | DTYMK | P23919 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3877266 | 0.88 | ACHE (0.40) | ACHEGPR119CKS1BSKP1SKP2 | |
| SCHEMBL13876151 | 0.81 | KCNH2 (0.44) | GPR119CKS1BSKP1SKP2KCNH2 | |
| SCHEMBL25338892 | 0.76 | KIT (0.46) | ACHEGPR119CKS1BSKP1SKP2 | |
| SCHEMBL2919286 | 0.76 | PDGFRB (0.62) | ACHEKCNH2KIT | |
| SCHEMBL13875886 | 0.74 | KCNH2 (0.44) | GPR119KCNH2KITRET | |
| SCHEMBL13876127 | 0.72 | CNR1 (0.44) | GPR119CKS1BSKP1SKP2KCNH2 | |
| SCHEMBL31652019 | 0.72 | POLB (0.55) | ACHEGPR119CKS1BSKP1SKP2 | |
| SCHEMBL13876153 | 0.72 | KIT (0.54) | ACHEGPR119CKS1BSKP1SKP2 | |
| SCHEMBL20607545 | 0.72 | AOC3 (0.54) | ACHEGPR119CKS1BSKP1SKP2 | |
| SCHEMBL31651589 | 0.70 | POLB (0.53) | ACHEGPR119CKS1BSKP1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524847-B2 | Fused 1,3-dihydro-imidazole ring compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |