Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.54 |
| ▸ | ACACB | O00763 | 14/20 | 0.46 |
| ▸ | ACACA | Q13085 | 8/20 | 0.45 |
| ▸ | GRN | P28799 | 2/20 | 0.45 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3689773 | 0.83 | OPRM1 (0.73) | OPRM1OPRD1OPRK1ACACBACACA | |
| SCHEMBL6685812 | 0.82 | OPRM1 (0.72) | OPRM1OPRD1OPRK1ACACBACACA | |
| SCHEMBL14457026 | 0.80 | GRM5 (0.50) | OPRM1OPRD1OPRK1GRNSORT1 | |
| SCHEMBL14456723 | 0.78 | GRM5 (0.50) | OPRM1OPRD1OPRK1GRNSORT1 | |
| SCHEMBL27549457 | 0.78 | OPRM1 (0.62) | OPRM1OPRD1OPRK1ACACBGRN | |
| SCHEMBL13876367 | 0.77 | LIPE (0.51) | OPRM1OPRD1OPRK1GRNSORT1 | |
| SCHEMBL13876381 | 0.77 | GRM5 (0.52) | OPRM1OPRD1OPRK1GRNSORT1 | |
| SCHEMBL13876362 | 0.77 | EPHX2 (0.55) | OPRM1OPRD1OPRK1GRNSORT1 | |
| SCHEMBL3700239 | 0.76 | OPRM1 (0.51) | OPRM1OPRD1OPRK1ACACBACACA | |
| SCHEMBL3694390 | 0.73 | OPRM1 (0.49) | OPRM1OPRD1OPRK1ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026305-A9 | DIARYL ETHERS AS OPIOID RECEPTOR ANTAGONIST | LILLY CO ELI (US) | 2004-05-13 | — | — | WO | disclosed |