Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 2/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | CCR8 | P51685 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.37 |
| ▸ | MPO | P05164 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | GRM5 | P41594 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21386765 | 0.87 | CCR1 (0.38) | NOS2NOS3CCR1CCR8SMN1; SMN2 | |
| SCHEMBL2010535 | 0.83 | CCR1 (0.44) | NOS2NOS3CCR1CCR8SMN1; SMN2 | |
| SCHEMBL17429701 | 0.78 | CCR1 (0.43) | NOS2NOS3CCR1CCR8SMN1; SMN2 | |
| SCHEMBL247492 | 0.78 | SMN1; SMN2 (0.44) | NOS2NOS3CCR1CCR8SMN1; SMN2 | |
| SCHEMBL943326 | 0.74 | — | — | |
| SCHEMBL904590 | 0.74 | — | — | |
| SCHEMBL29792015 | 0.74 | — | — | |
| SCHEMBL24916774 | 0.73 | CCR1 (0.52) | NOS2NOS3CCR1CCR8SMN1; SMN2 | |
| SCHEMBL14082023 | 0.73 | CCR1 (0.52) | NOS2NOS3CCR1CCR8SMN1; SMN2 | |
| SCHEMBL30201993 | 0.73 | CCR1 (0.52) | NOS2NOS3CCR1CCR8SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1548029-B1 | Peptid- and peptide mimetic derivatives having integrin inhibitor properties III | BIOMET DEUTSCHLAND GMBH (DE) | 2009-04-15 | — | — | EP | disclosed |