Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17138149 | 0.91 | HIF1A (0.49) | ADRB2ADRB1TSHR | |
| SCHEMBL10154613 | 0.86 | ADRB2 (0.56) | ADRB2ADRB1ACHEKMT2AMEN1 | |
| SCHEMBL9123406 | 0.83 | ADRB2 (0.62) | ADRB2ADRB1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL27330236 | 0.82 | LMNA (0.57) | LMNA | |
| SCHEMBL3723068 | 0.82 | ADRB2 (0.59) | ADRB2ADRB1ACHEKMT2AMEN1 | |
| SCHEMBL17277599 | 0.81 | SCN4A (0.59) | ADRB2ADRB1ACHEKMT2AMEN1 | |
| SCHEMBL20082442 | 0.81 | SCN4A (0.59) | ADRB2ADRB1ACHEKMT2AMEN1 | |
| SCHEMBL15958920 | 0.81 | ADRB2 (0.59) | ADRB2ADRB1ACHEKMT2AMEN1 | |
| SCHEMBL6281442 | 0.80 | HIF1A (0.40) | ADRB2ADRB1SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL2561288 | 0.80 | ENPP2 (0.50) | ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2050734-A1 | PENTADIENAMIDE DERIVATIVE | Kyowa Hakko Kirin Co., Ltd. (JP) | 2009-04-22 | — | — | EP | disclosed |