Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | GPR88 | Q9GZN0 | 8/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13879749 | 0.91 | ADRB2 (0.54) | TSHRADRB2ADRB1 | |
| SCHEMBL27330236 | 0.86 | LMNA (0.57) | GPR88 | |
| SCHEMBL2561288 | 0.84 | ENPP2 (0.50) | HIF1AADRB2ADRB1GPR88 | |
| SCHEMBL6281442 | 0.84 | HIF1A (0.40) | HIF1AGPBAR1TSHRMAPK1ADRB2 | |
| SCHEMBL17138170 | 0.84 | GPBAR1 (0.60) | HIF1AGPBAR1TSHRMAPK1MTNR1A | |
| SCHEMBL201166 | 0.82 | PARP1 (0.53) | ADRB2ADRB1GPR88 | |
| SCHEMBL19291801 | 0.81 | TAAR1 (0.44) | GPR88 | |
| SCHEMBL17138148 | 0.79 | HIF1A (0.47) | HIF1AGPBAR1TSHRMAPK1MTNR1A | |
| SCHEMBL14595237 | 0.78 | TSHR (0.59) | HIF1AGPBAR1TSHRMAPK1MTNR1A | |
| SCHEMBL2967940 | 0.77 | TRIM24 (0.55) | HIF1ATSHRMAPK1MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150283051-A1 | DERIVATIVE OF NOVEL POLYHYDROXY AROMATIC COMPOUND AND USE THEREOF | RNS CO.,LTD. (KR) | 2015-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150283051-A1 | DERIVATIVE OF NOVEL POLYHYDROXY AROMATIC COMPOUND AND USE THEREOF | HRH3, CBR3, H1-0 | HIF1A 375/4885GPBAR1 3596/4885TSHR 4026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.