Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | CASP2 | P42575 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13640252 | 0.92 | FAAH (0.47) | FAAHNAMPTCASP2MEN1KMT2A | |
| SCHEMBL13640275 | 0.88 | GLP1R (0.46) | FAAHNAMPTALDH1A1TSHRCASP1 | |
| SCHEMBL13640253 | 0.87 | FAAH (0.53) | FAAHCASP2MEN1KMT2APAOX | |
| SCHEMBL25727448 | 0.86 | KDM4E (0.59) | FAAHNAMPTCASP2MEN1KMT2A | |
| SCHEMBL13640257 | 0.84 | FAAH (0.50) | FAAHCASP2PAOXNAAATSHR | |
| SCHEMBL17167854 | 0.84 | FAAH (0.46) | FAAHCASP2MEN1KMT2APAOX | |
| SCHEMBL23713358 | 0.84 | FAAH (0.66) | FAAHNAMPTCASP2MEN1KMT2A | |
| SCHEMBL19634436 | 0.84 | FAAH (0.66) | FAAHNAMPTCASP2MEN1KMT2A | |
| SCHEMBL22526314 | 0.84 | KDM4E (0.56) | FAAHNAMPTCASP2MEN1KMT2A | |
| SCHEMBL19634653 | 0.84 | FAAH (0.66) | FAAHNAMPTCASP2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9708383-B2 | Double-acylated GLP-1 derivatives | NOVO NORDISK A/S (DK) | 2017-07-18 | — | — | US | disclosed |
| US-20130288960-A1 | Double-Acylated GLP-1 Derivatives | NOVO NORDISK A/S (DK) | 2013-10-31 | — | — | US | disclosed |
| US-20090111730-A1 | Polypeptide protracting tags | NOVO NORDISK A/S (DK) | 2009-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130288960-A1 | Double-Acylated GLP-1 Derivatives | GLP1R, VIP, IAPP | FAAH 773/4885NAMPT 4192/4885CASP2 615/4885 |
| US-20090111730-A1 | Polypeptide protracting tags | LNPEP, FGB, ENPEP | FAAH 2903/4885NAMPT 2780/4885CASP2 2710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.