SCHEMBL13888317

SCHEMBL13888317

C=COCCOc1ccc(C(C)N)cc1

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 2/20 0.39
PSMB1 P20618 1/20 0.39
PSMB5 P28074 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ADRB2 P07550 1/20 0.37
HRH3 Q9Y5N1 2/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
GAA P10253 1/20 0.35
HTT P42858 1/20 0.35
CHRNB2 P17787 1/20 0.34
CHRNB4 P30926 1/20 0.34
CHRNA3 P32297 1/20 0.34
CHRNA7 P36544 1/20 0.34
CHRNA4 P43681 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21610572 0.86 KMT2A (0.47) PSMB1PSMB5TDP1MEN1KMT2A
SCHEMBL26312618 0.82 HRH3 (0.40) SLC2A1PSMB1PSMB5TDP1HRH3
SCHEMBL26312614 0.82 HRH3 (0.37) SLC2A1PSMB1PSMB5TDP1HRH3
SCHEMBL419937 0.82 THRB (0.41) TDP1HTTCHRNB2CHRNB4CHRNA3
SCHEMBL13888299 0.77 CA12 (0.50) ADRB2MEN1KMT2AGAA
SCHEMBL16364692 0.77 SLC2A1 (0.60) SLC2A1
SCHEMBL720020 0.77 DRD2 (0.48) MEN1KMT2AHTT
SCHEMBL11788154 0.77 SMN1; SMN2 (0.47) TDP1KMT2ACHRNB4CHRNA3CHRNA7
SCHEMBL8285038 0.77 SLC2A1 (0.51) SLC2A1
SCHEMBL13888325 0.77 TDP1 (0.48) TDP1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7524977-B2 Process for producing fluoroalkanesulfonamide derivatives CENTRAL GLASS COMPANY, LIMITED (JP) 2009-04-28 US disclosed
US-7524977-B2 Process for producing fluoroalkanesulfonamide derivatives CENTRAL GLASS COMPANY, LIMITED (JP) 2009-04-28 US disclosed
US-20080058538-A1 Process for producing fluoroalkanesulfonamide derivatives CENTRAL GLASS COMPANY, LIMITED (JP) 2008-03-06 US disclosed
US-20080058538-A1 Process for producing fluoroalkanesulfonamide derivatives CENTRAL GLASS COMPANY, LIMITED (JP) 2008-03-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080058538-A1 Process for producing fluoroalkanesulfonamide derivatives AFF1, AFF2, RER1 SLC2A1 4453/4885PSMB1 3493/4885PSMB5 3604/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.