Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 17/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14413280 | 0.90 | BRD4 (0.49) | PTGS2PTGS1BRD4KIF11 | |
| SCHEMBL7946495 | 0.85 | LMNA (0.49) | PTGS2BRD4 | |
| SCHEMBL13873024 | 0.84 | RORC (0.48) | PTGS2PTGS1 | |
| SCHEMBL12603833 | 0.81 | PTGS2 (0.47) | PTGS2PTGS1BRD4KIF11 | |
| SCHEMBL12603775 | 0.80 | AHR (0.50) | KIF11 | |
| SCHEMBL458111 | 0.78 | ESR2 (0.52) | PTGS2 | |
| SCHEMBL19323707 | 0.78 | AKR1C2 (0.45) | — | |
| SCHEMBL13995358 | 0.77 | BRD4 (0.52) | PTGS2BRD4 | |
| SCHEMBL904087 | 0.77 | ESR2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL8055957 | 0.77 | PTGS2 (0.77) | PTGS2PTGS1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090111791-A1 | Soluble Epoxide Hydrolase Inhibitors and Methods of Using Same | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090111791-A1 | Soluble Epoxide Hydrolase Inhibitors and Methods of Using Same | EPHX1, EPHX2, NCEH1 | PTGS2 85/4885PTGS1 59/4885BRD4 3793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.