Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 4/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.50 |
| ▸ | DPP9 | Q86TI2 | 5/20 | 0.49 |
| ▸ | DPP4 | P27487 | 5/20 | 0.49 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.49 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | CCR3 | P51677 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30261110 | 0.93 | ALDH1A1 (0.51) | ALDH1A1HPGDSMN1; SMN2ESR1ESR2 | |
| SCHEMBL3660060 | 0.86 | DPP9 (0.58) | DPP9DPP4DPP8DPP7 | |
| SCHEMBL25605602 | 0.85 | NOTUM (0.63) | ALDH1A1HPGDSMN1; SMN2ESR1ESR2 | |
| SCHEMBL23335841 | 0.83 | L3MBTL1 (0.54) | ALDH1A1HPGDSMN1; SMN2ESR1ESR2 | |
| SCHEMBL19932177 | 0.82 | DPP4 (0.52) | ALDH1A1HPGDSMN1; SMN2ESR1ESR2 | |
| SCHEMBL3171430 | 0.81 | ESR2 (0.68) | ESR1ESR2NOTUMMEN1KMT2A | |
| SCHEMBL381428 | 0.80 | NR1H2 (0.56) | SMN1; SMN2ESR1ESR2NPC1RAB9A | |
| SCHEMBL587507 | 0.80 | ABHD6 (0.59) | HPGDSMN1; SMN2ESR1ESR2DPP9 | |
| SCHEMBL2573737 | 0.80 | ADRA1A (0.52) | ALDH1A1DPP9DPP4DPP8NOTUM | |
| SCHEMBL2930510 | 0.80 | ESR2 (0.54) | ESR1ESR2DPP4DPP7NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8575158-B2 | 1-phenyl-substituted heterocyclyl derivatives and their use as prostaglandin D2 receptor modulators | ACTELION PHARMACEUTICALS LTD. (CH) | 2013-11-05 | — | — | US | disclosed |
| US-20090111982-A1 | MACROCYCLIC COMPOUNDS AS INHIBITORS OF VIRAL REPLICATION | HOFFMANN-LA ROCHE INC. | 2009-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090111982-A1 | MACROCYCLIC COMPOUNDS AS INHIBITORS OF VIRAL REPLICATION | EIF2AK2, HAVCR2, ZC3HAV1 | ALDH1A1 2109/4885HPGD 2920/4885SMN1; SMN2 748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.