Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 6/20 | 0.35 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.32 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.32 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.32 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.32 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2552557 | 0.87 | LMNA (0.35) | HRH3LMNAKCNQ3KCNQ2 | |
| SCHEMBL4023156 | 0.80 | GNAI3 (0.38) | BCHEGNAI3GNAO1GNAI1HRH3 | |
| SCHEMBL8971073 | 0.80 | SIGMAR1 (0.46) | HRH3LMNAKMT2ACHRM2 | |
| SCHEMBL2116384 | 0.78 | HRH3 (0.37) | BCHEGNAI3GNAO1GNAI1HRH3 | |
| SCHEMBL9815993 | 0.78 | GNAO1 (0.56) | GNAI3GNAO1GNAI1CHRM3 | |
| SCHEMBL8971344 | 0.77 | KCNA3 (0.38) | GNAI3GNAO1GNAI1HRH3 | |
| SCHEMBL26745710 | 0.77 | GNAO1 (0.59) | GNAI3GNAO1GNAI1 | |
| SCHEMBL1463883 | 0.77 | GNAI3 (0.42) | GNAI3GNAO1GNAI1CHRM3 | |
| SCHEMBL26511089 | 0.77 | GNAO1 (0.59) | GNAI3GNAO1GNAI1 | |
| SCHEMBL7285791 | 0.77 | GNAI3 (0.55) | GNAI3GNAO1GNAI1HRH3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700383-A1 | NOVEL 1-PHENYLALKANONE 5-HT 4? RECEPTOR LIGANDS | SYNTEX (U.S.A.) INC. (US) | 1996-03-13 | — | — | EP | disclosed |