Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13897075 | 0.85 | DGAT1 (0.33) | CA14 | |
| SCHEMBL4986712 | 0.83 | HDAC6 (0.37) | CA14 | |
| SCHEMBL12201068 | 0.80 | CA14 (0.42) | CA14 | |
| SCHEMBL29139788 | 0.76 | TSHR (0.34) | CA14 | |
| SCHEMBL17787172 | 0.74 | MEN1 (0.49) | — | |
| SCHEMBL2128079 | 0.74 | TSHR (0.50) | HMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL1626498 | 0.72 | HDAC6 (0.40) | CA14 | |
| SCHEMBL15083136 | 0.72 | CA14 (0.35) | CA14 | |
| SCHEMBL16574588 | 0.72 | CTSS (0.31) | — | |
| SCHEMBL15083257 | 0.70 | CA14 (0.40) | CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7507420-B2 | Peptidyl prodrugs and linkers and stabilizers useful therefor | MEDAREX, INC. (US) | 2009-03-24 | — | — | US | disclosed |
| US-7507420-B2 | Peptidyl prodrugs and linkers and stabilizers useful therefor | MEDAREX, INC. (US) | 2009-03-24 | — | — | US | disclosed |