SCHEMBL29139788

SCHEMBL29139788

CC(C)(C)OC(=O)N(CCSSCCN)C(=O)OC(C)(C)C

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.34
THPO P40225 1/20 0.34
MAPT P10636 2/20 0.33
EHMT2 Q96KQ7 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
HDAC6 Q9UBN7 3/20 0.33
HDAC1 Q13547 2/20 0.33
HDAC2 Q92769 2/20 0.33
HDAC3 O15379 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
CA14 Q9ULX7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4986712 0.91 HDAC6 (0.37) HDAC6HDAC1HDAC2HDAC3HDAC8
SCHEMBL19133186 0.85 TSHR (0.33) TSHRTHPOMAPTEHMT2TDP1
SCHEMBL28319882 0.81 HDAC6 (0.37) HDAC6HDAC1HDAC2CA14
SCHEMBL21784320 0.77 CA14 (0.41) HDAC6HDAC1HDAC2CA14
SCHEMBL6512969 0.76 CA12 (0.32) CA14
SCHEMBL6512974 0.76 HDAC3 (0.30) HDAC6HDAC1HDAC2HDAC3HDAC8
SCHEMBL13897101 0.76 CA14 (0.33) CA14
SCHEMBL865291 0.75 HDAC6 (0.40) TDP1HDAC6HDAC1HDAC2CA14
SCHEMBL343348 0.75 HDAC6 (0.40) TDP1HDAC6HDAC1HDAC2CA14
SCHEMBL1906455 0.75 HDAC6 (0.40) TDP1HDAC6HDAC1HDAC2CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117025286-B Modified high-bearing gear oil and production process thereof 山东北方淄特特种油股份有限公司 2023-12-08 CN claimed
EP-4572795-A2 METHODS AND COMPOSITIONS FOR TREATING CANCER WITH CANCER-BINDING ADJUVANTS The University of Chicago (US) 2025-06-25 EP disclosed
US-20250122502-A1 Bifunctional Molecules and Methods of Using Thereof FLAGSHIP PIONEERING, INC. (US) 2025-04-17 US disclosed
US-20250114441-A1 POLYMERIC VACCINE FOR OPIOID ADDICTION THE JOHNS HOPKINS UNVERSITY 2025-04-10 US disclosed
US-20240400684-A1 ANTIBODY-MEDIATED DELIVERY OF CAS9 TO MAMMALIAN CELLS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2024-12-05 US disclosed
WO-2024040169-A2 METHODS AND COMPOSITIONS FOR TREATING CANCER WITH CANCER-BINDING ADJUVANTS THE UNIVERSITY OF CHICAGO (US) 2024-02-22 WO disclosed
CN-117025286-B Modified high-bearing gear oil and production process thereof 山东北方淄特特种油股份有限公司 2023-12-08 CN disclosed
CN-117025286-A Modified high-bearing gear oil and production process thereof 山东北方淄特特种油股份有限公司 2023-11-10 CN disclosed
US-20230332145-A1 BIFUNCTIONAL MOLECULES AND METHODS OF USING THEREOF FLAGSHIP PIONEERING, INC. (US) 2023-10-19 US disclosed
US-20230167450-A1 BIFUNCTIONAL MOLECULES AND METHODS OF USING THEREOF FLAGSHIP PIONEERING, INC. (US) 2023-06-01 US disclosed
CN-115996755-A Bifunctional molecules and methods of use thereof 旗舰创业创新VI有限责任公司 2023-04-21 CN disclosed
WO-2023049816-A2 BIFUNCTIONAL MOLECULES AND METHODS OF USING THEREOF FLAGSHIP PIONEERING, INC. (US) 2023-03-30 WO disclosed
EP-4138858-A1 BIFUNCTIONAL MOLECULES AND METHODS OF USING THEREOF Flagship Pioneering, Inc. (US) 2023-03-01 EP disclosed
EP-4138857-A1 BIFUNCTIONAL MOLECULES AND METHODS OF USING THEREOF Flagship Pioneering, Inc. (US) 2023-03-01 EP disclosed
EP-4126063-A1 BIFUNCTIONAL MOLECULES AND METHODS OF USING THEREOF Flagship Pioneering, Inc. (US) 2023-02-08 EP disclosed
US-11484599-B2 Polymer conjugate vaccines THE UNIVERSITY OF CHICAGO (US) 2022-11-01 US disclosed
CN-108770357-B Polymer conjugate vaccines 芝加哥大学 2022-10-28 CN disclosed
US-20220305135-A1 METHODS AND COMPOSITIONS FOR TREATING CANCER WITH CANCER-TARGETED ADJUVANTS THE UNIVERSITY OF CHICAGO (US) 2022-09-29 US disclosed
EP-3976061-A1 METHODS AND COMPOSITIONS FOR TREATING CANCER WITH CANCER-TARGETED ADJUVANTS The University of Chicago (US) 2022-04-06 EP disclosed
CN-114206355-A Methods and compositions for treating cancer with cancer-targeting adjuvants 芝加哥大学 2022-03-18 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11484599-B2 Polymer conjugate vaccines CD14, TLR3, TLR1 TSHR 1379/4885THPO 458/4885MAPT 1182/4885
US-20220305135-A1 METHODS AND COMPOSITIONS FOR TREATING CANCER WITH CANCER-TARGETED ADJUVANTS TLR3, TLR6, TLR2 TSHR 2525/4885THPO 306/4885MAPT 3512/4885
US-20250114441-A1 POLYMERIC VACCINE FOR OPIOID ADDICTION OPRM1, OPRK1, OPRL1 TSHR 1132/4885THPO 3701/4885MAPT 386/4885
US-20230332145-A1 BIFUNCTIONAL MOLECULES AND METHODS OF USING THEREOF EFTUD2, DDX21, SNRPE TSHR 3164/4885THPO 4337/4885MAPT 4546/4885
US-20250122502-A1 Bifunctional Molecules and Methods of Using Thereof EFTUD2, DDX21, SNRPE TSHR 3164/4885THPO 4337/4885MAPT 4546/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.