SCHEMBL13899557

SCHEMBL13899557

CCC(C)(C)C(=O)C1CCCCC1

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.42
HSD17B10 Q99714 1/20 0.42
CES2 O00748 1/20 0.42
CES1 P23141 1/20 0.42
HSD11B1 P28845 1/20 0.39
CCR2 P41597 1/20 0.38
NAAA Q02083 1/20 0.38
RECQL P46063 2/20 0.38
FKBP1A P62942 3/20 0.37
ALDH1A1 P00352 3/20 0.37
HDAC8 Q9BY41 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37
TSHR P16473 2/20 0.35
EPHX1 P07099 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19367986 0.98 SMN1; SMN2 (0.44) SMN1; SMN2HSD17B10CES2CES1HSD11B1
SCHEMBL21099781 0.89 RIPK1 (0.36) SMN1; SMN2HSD17B10HSD11B1CCR2FKBP1A
SCHEMBL21186856 0.89 RIPK1 (0.36) SMN1; SMN2HSD17B10HSD11B1CCR2FKBP1A
SCHEMBL19223961 0.89 RIPK1 (0.36) SMN1; SMN2HSD17B10HSD11B1CCR2FKBP1A
SCHEMBL21703733 0.83 RIPK1 (0.33) SMN1; SMN2HSD17B10HSD11B1CCR2FKBP1A
SCHEMBL23251132 0.81 CCR2 (0.42) SMN1; SMN2HSD17B10CES2CES1HSD11B1
SCHEMBL12672198 0.81 SMN1; SMN2 (0.41) SMN1; SMN2HSD17B10CES2CES1HSD11B1
SCHEMBL19772908 0.78 THRA (0.53)
SCHEMBL22060690 0.77 CES2 (0.50) SMN1; SMN2HSD17B10CES2CES1HSD11B1
SCHEMBL13246768 0.77 CES2 (0.50) SMN1; SMN2HSD17B10CES2CES1HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7504194-B2 Resin showing an increase in solubility in alkali developer by action of an acid, a compound being capable of generating an acid when irradiated with an actinic ray or radiation, an acrylic resin with silicon-containing units and being stable to acids but insoluble in alkali developer, solvent FUJIFILM CORPORATION (JP) 2009-03-17 US disclosed
US-7504194-B2 Resin showing an increase in solubility in alkali developer by action of an acid, a compound being capable of generating an acid when irradiated with an actinic ray or radiation, an acrylic resin with silicon-containing units and being stable to acids but insoluble in alkali developer, solvent FUJIFILM CORPORATION (JP) 2009-03-17 US disclosed
US-20070134590-A1 Resin showing an increase in solubility in alkali developer by action of an acid, a compound being capable of generating an acid when irradiated with an actinic ray or radiation, an acrylic resin with silicon-containing units and being stable to acids but insoluble in alkali developer, solvent FUJIFILM CORPORATION. (JP) 2007-06-14 US disclosed
US-20070134590-A1 Resin showing an increase in solubility in alkali developer by action of an acid, a compound being capable of generating an acid when irradiated with an actinic ray or radiation, an acrylic resin with silicon-containing units and being stable to acids but insoluble in alkali developer, solvent FUJIFILM CORPORATION. (JP) 2007-06-14 US disclosed