SCHEMBL16786336

SCHEMBL16786336

CCCCCCCCn1c2ccc(C)cc2c(=O)c2cc3c(cc21)c(=O)c1cc(C)ccc1n3CCCCCCCC

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RORA P35398 2/20 0.57
RORC P51449 2/20 0.57
RORB Q92753 2/20 0.57
PGR P06401 1/20 0.57
CSF1R P07333 1/20 0.49
TLR8 Q9NR97 2/20 0.48
PSEN1 P49768 4/20 0.47
PSEN2 P49810 4/20 0.47
APH1B Q8WW43 4/20 0.47
NCSTN Q92542 4/20 0.47
APH1A Q96BI3 4/20 0.47
PSENEN Q9NZ42 4/20 0.47
SMN1; SMN2 Q16637 3/20 0.46
MAPT P10636 3/20 0.46
RXFP1 Q9HBX9 2/20 0.46
THRB P10828 1/20 0.46
SLC6A4 P31645 2/20 0.45
SLC6A2 P23975 1/20 0.45
HRH1 P35367 1/20 0.45
CNR2 P34972 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13471984 0.97 RORA (0.59) RORARORCRORBPGRCSF1R
SCHEMBL20094723 0.95 RORA (0.52) RORARORCRORBPGRCSF1R
SCHEMBL17190827 0.94 RORA (0.63) RORARORCRORBPGRCSF1R
SCHEMBL13125230 0.91 RORA (0.58) RORARORCRORBPGRTLR8
SCHEMBL12284774 0.88 RORA (0.61) RORARORCRORBPGRTLR8
SCHEMBL12593202 0.88 RORA (0.61) RORARORCRORBPGRTLR8
SCHEMBL13503151 0.88 RORA (0.61) RORARORCRORBPGRTLR8
SCHEMBL804880 0.88 RORA (0.61) RORARORCRORBPGRTLR8
SCHEMBL15396934 0.88 RORA (0.61) RORARORCRORBPGRTLR8
SCHEMBL14261677 0.88 RORA (0.61) RORARORCRORBPGRTLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10457694-B2 Compound and organic photoelectronic device and image sensor SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-10-29 US disclosed
US-10256414-B2 Organic photoelectronic device and image sensor SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-04-09 US disclosed
US-20180111952-A1 COMPOUND AND ORGANIC PHOTOELECTRONIC DEVICE AND IMAGE SENSOR SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-04-26 US disclosed
US-20180111952-A1 COMPOUND AND ORGANIC PHOTOELECTRONIC DEVICE AND IMAGE SENSOR SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-04-26 US disclosed
US-9884877-B2 Compound and organic photoelectronic device and image sensor SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-02-06 US disclosed
US-9884877-B2 Compound and organic photoelectronic device and image sensor SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-02-06 US disclosed
US-20150303378-A1 COMPOUND AND ORGANIC PHOTOELECTRONIC DEVICE AND IMAGE SENSOR SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-10-22 US disclosed
US-20150162548-A1 ORGANIC PHOTOELECTRONIC DEVICE AND IMAGE SENSOR SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-06-11 US disclosed
US-20150162548-A1 ORGANIC PHOTOELECTRONIC DEVICE AND IMAGE SENSOR SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-06-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180111952-A1 COMPOUND AND ORGANIC PHOTOELECTRONIC DEVICE AND IMAGE SENSOR ASIC1, NCS1, PIEZO1 RORA 2987/4885RORC 3570/4885RORB 3176/4885
US-10457694-B2 Compound and organic photoelectronic device and image sensor ASIC1, NCS1, PIEZO1 RORA 2987/4885RORC 3570/4885RORB 3176/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.