SCHEMBL8086740

SCHEMBL8086740

CCCCn1c2ccccc2c(=O)c2cc(Cl)ccc21

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RORA P35398 5/20 0.55
RORC P51449 5/20 0.55
RORB Q92753 5/20 0.55
PGR P06401 4/20 0.55
TP53 P04637 2/20 0.54
ALDH1A1 P00352 2/20 0.53
SLC6A4 P31645 2/20 0.52
SLC6A2 P23975 1/20 0.52
HRH1 P35367 1/20 0.52
MAPT P10636 1/20 0.52
PSEN1 P49768 1/20 0.51
PSEN2 P49810 1/20 0.51
APH1B Q8WW43 1/20 0.51
NCSTN Q92542 1/20 0.51
APH1A Q96BI3 1/20 0.51
PSENEN Q9NZ42 1/20 0.51
NPC1 O15118 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
NR1H2 P55055 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29543602 1.00 RORA (0.55) RORARORCRORBPGRTP53
SCHEMBL20291531 0.92 ALDH1A1 (0.54) PGRTP53ALDH1A1SLC6A4SLC6A2
SCHEMBL29660662 0.92 ALDH1A1 (0.54) PGRTP53ALDH1A1SLC6A4SLC6A2
SCHEMBL1923371 0.88 PSEN1 (0.63) RORARORCRORBPGRALDH1A1
SCHEMBL29654225 0.87 RORA (0.62) RORARORCRORBPGRTP53
SCHEMBL14493936 0.87 RORA (0.62) RORARORCRORBPGRTP53
SCHEMBL10730998 0.87 PGR (0.70) RORARORCRORBPGRALDH1A1
SCHEMBL8086738 0.85 ALDH1A1 (0.72) TP53ALDH1A1MAPTTDP1L3MBTL1
SCHEMBL13899693 0.84 PSEN1 (0.66) RORARORCRORBPSEN1PSEN2
SCHEMBL8085590 0.84 PGR (0.71) RORARORCRORBPGRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4400558-A1 PHOTON UPCONVERSION COMPOSITION, FILM, MYOPIA-SUPPRESSING TRANSPARENT PRODUCT, AND METHOD FOR CONVERTING VISIBLE LIGHT INTO ULTRAVIOLET LIGHT Kyushu University, National University Corporation (JP) 2024-07-17 EP disclosed
CN-117980438-A Photon up-conversion composition, film, myopia-inhibiting transparent product and method for converting visible light into ultraviolet light 国立大学法人九州大学 2024-05-03 CN disclosed
US-11726404-B2 Spontaneous-emission type photosensitive resin composition, color filter manufactured using same, and image display apparatus DONGWOO FINE-CHEM CO., LTD. (KR) 2023-08-15 US disclosed
EP-3339331-B1 COMPOSITION ADEKA CORP (JP) 2022-02-16 EP disclosed
EP-3431557-B1 COMPOSITION, CURED PRODUCT, IMAGE FORMING APPARATUS, AND IMAGE FORMING METHOD RICOH CO LTD (JP) 2022-01-12 EP disclosed
CN-109312051-B Epoxy (meth) acrylate resin and resist member DIC株式会社 2021-07-09 CN disclosed
US-10858527-B2 Composition, cured product, image forming apparatus, and image forming method RICOH COMPANY, LTD. (JP) 2020-12-08 US disclosed
EP-3434494-B1 IMAGE FORMING METHOD KONICA MINOLTA INC (JP) 2020-10-28 EP disclosed
US-10731062-B2 Gas-generating material and micropump SEKISUI CHEMICAL CO., LTD. (JP) 2020-08-04 US disclosed
US-20200148901-A1 IMAGE FORMING METHOD Konica Minolta, Inc. (JP) 2020-05-14 US disclosed
CN-101135852-A Pattern forming material and method FUJIFILM CORP (JP) 2008-03-05 CN disclosed
US-20080020323-A1 Light sensitive planographic printing plate material KONICA MINOLTA MEDICAL & GRAPHIC, INC. 2008-01-24 US disclosed
US-20080020323-A1 Light sensitive planographic printing plate material KONICA MINOLTA MEDICAL & GRAPHIC, INC. 2008-01-24 US disclosed
CN-101052918-A Photosensitive composition, pattern forming material, photosensitive laminate, pattern forming apparatus, and pattern forming method FUJIFILM CORP (JP) 2007-10-10 CN disclosed
CN-101010636-A Pattern forming material, pattern forming apparatus, and pattern forming method FUJI FILM CORP (JP) 2007-08-01 CN disclosed
CN-1934502-A Pattern forming method and pattern FUJI PHOTO FILM CO LTD (JP) 2007-03-21 CN disclosed
US-6054501-A CURABILITY; GLOSSINESS; CAN BE BLENDED WITH INKS, PAINTS NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2000-04-25 US disclosed
US-5776658-A PHOTOINITIATOR CONTAINING SILICON AND KETONE GROUP AGFA-GEVAERT AG (DE) 1998-07-07 US disclosed
EP-0844255-A1 PHOTOPOLYMERIZATION INITIATOR AND ACTINIC RADIATION-CURABLE COMPOSITION COMPRISING THE SAME NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1998-05-27 EP disclosed
EP-0705865-A1 Photoinitiators compatible with silicones and photosensitive compositions containing the same HOECHST AKTIENGESELLSCHAFT (DE) 1996-04-10 EP disclosed