Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | RORC | P51449 | 4/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17856924 | 1.00 | PTPN1 (0.38) | PTPN1RORCCA2MCOLN3GPR35 | |
| SCHEMBL17856888 | 0.89 | GPR35 (0.43) | PTPN1RORCCA2MCOLN3GPR35 | |
| SCHEMBL255379 | 0.89 | GPR35 (0.52) | PTPN1RORCCA2MCOLN3GPR35 | |
| SCHEMBL140432 | 0.89 | GPR35 (0.52) | PTPN1RORCCA2MCOLN3GPR35 | |
| SCHEMBL16153619 | 0.88 | MCOLN3 (0.34) | PTPN1MCOLN3MAPTALDH1A1HPGD | |
| SCHEMBL19393227 | 0.84 | CA2 (0.38) | PTPN1RORCCA2MCOLN3MAPT | |
| SCHEMBL17861116 | 0.82 | GPR35 (0.52) | PTPN1RORCCA2GPR35MAPT | |
| SCHEMBL140675 | 0.82 | GPR35 (0.52) | PTPN1RORCCA2GPR35MAPT | |
| SCHEMBL17856889 | 0.82 | GPR35 (0.43) | PTPN1RORCCA2GPR35MAPT | |
| SCHEMBL14000916 | 0.81 | RAB9A (0.38) | MAPTMEN1KMT2APOLBGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058501-A1 | OXIDIZED GLUTATHIONE ASSAY | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2012-03-08 | — | — | US | disclosed |