Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 8/20 | 0.49 |
| ▸ | PLD2 | O14939 | 7/20 | 0.48 |
| ▸ | PLD1 | Q13393 | 7/20 | 0.48 |
| ▸ | YEATS4 | O95619 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | MLLT3 | P42568 | 1/20 | 0.46 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.46 |
| ▸ | YEATS2 | Q9ULM3 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18477021 | 0.89 | ALDH1A1 (0.58) | ALDH1A1MAPK1USP2LMNAHSD11B1 | |
| SCHEMBL13899718 | 0.86 | USP2 (0.52) | ALDH1A1USP2LMNAHSD11B1PLD2 | |
| SCHEMBL5837066 | 0.86 | ALDH1A1 (0.62) | ALDH1A1MAPK1USP2LMNAHSD11B1 | |
| SCHEMBL13153970 | 0.86 | HSD11B1 (0.55) | ALDH1A1MAPK1USP2LMNAHSD11B1 | |
| SCHEMBL7184792 | 0.84 | ALDH1A1 (0.54) | ALDH1A1MAPK1USP2LMNAHSD11B1 | |
| SCHEMBL7184789 | 0.84 | ALDH1A1 (0.54) | ALDH1A1MAPK1USP2LMNAHSD11B1 | |
| SCHEMBL13153966 | 0.84 | ALDH1A1 (0.57) | ALDH1A1MAPK1USP2LMNAHSD11B1 | |
| SCHEMBL13908395 | 0.83 | PLD2 (0.48) | ALDH1A1USP2LMNAHSD11B1PLD2 | |
| Hydrochloric Acid SCHEMBL29848399 | 0.83 | ALDH1A1 (0.56) | ALDH1A1MAPK1USP2LMNAHSD11B1 | |
| SCHEMBL13801270 | 0.82 | HSD11B1 (0.58) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7498325-B2 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | KARL THOMAS GMBH (DE) | 2009-03-03 | — | — | US | disclosed |