Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.61 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | GRM5 | P41594 | 4/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9610050 | 0.95 | APP (0.55) | NOTUMCYP1A1CYP1A2CYP1B1KCNH2 | |
| SCHEMBL13900784 | 0.91 | NOTUM (0.61) | NOTUMCYP1A1CYP1A2CYP1B1KCNH2 | |
| SCHEMBL9610040 | 0.91 | MAPT (0.53) | NOTUMCYP1A1CYP1A2CYP1B1APP | |
| SCHEMBL13219274 | 0.88 | MAPT (0.58) | NOTUMCYP1A1CYP1A2CYP1B1GRM5 | |
| SCHEMBL17224548 | 0.88 | APP (0.63) | NOTUMAPPGRM5FFAR1PIK3CD | |
| SCHEMBL30718530 | 0.85 | MAPT (0.61) | NOTUMCYP1A1CYP1A2CYP1B1APP | |
| SCHEMBL2925968 | 0.85 | APP (0.67) | NOTUMCYP1A2APPGRM5FFAR1 | |
| SCHEMBL7261719 | 0.84 | MAPT (0.46) | NOTUMCYP1A1CYP1A2CYP1B1GRM5 | |
| SCHEMBL4324850 | 0.84 | ASIC3 (0.53) | NOTUMKCNH2APPGRM5PIK3CD | |
| SCHEMBL5886608 | 0.83 | APP (0.71) | CYP1A1CYP1A2CYP1B1KCNH2APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140194605-A1 | SERS Reporter Molecules and Methods | CABOT SECURITY MATERIALS, INC. (US) | 2014-07-10 | — | — | US | disclosed |
| US-20120156491-A1 | SERS Reporter Molecules and Methods | CABOT SECURITY MATERIALS INC. (US) | 2012-06-21 | — | — | US | disclosed |
| US-20120156491-A1 | SERS Reporter Molecules and Methods | CABOT SECURITY MATERIALS INC. (US) | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140194605-A1 | SERS Reporter Molecules and Methods | SRRT, MYCBP, SPR | NOTUM 4040/4885CYP1A1 839/4885CYP1A2 1660/4885 |
| US-20120156491-A1 | SERS Reporter Molecules and Methods | SRRT, MYCBP, SPR | NOTUM 4040/4885CYP1A1 839/4885CYP1A2 1660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.