Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | TNF | P01375 | 1/20 | 0.47 |
| ▸ | CDK4 | P11802 | 1/20 | 0.47 |
| ▸ | CCND1 | P24385 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MLYCD | O95822 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | LIMK2 | P53671 | 2/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5678625 | 0.86 | HSD11B1 (0.49) | HSD11B1TNFCDK4CCND1KMT2A | |
| SCHEMBL11210779 | 0.83 | KMT2A (0.56) | HSD11B1TNFCDK4CCND1KMT2A | |
| SCHEMBL4362033 | 0.82 | HSD11B1 (0.43) | HSD11B1KMT2AMEN1LTA4H | |
| Benzene SCHEMBL27406951 | 0.79 | HDAC6 (0.48) | HSD11B1TNFCDK4CCND1KMT2A | |
| SCHEMBL8641718 | 0.78 | HDAC6 (0.59) | CDK4CCND1KMT2AMEN1MLYCD | |
| SCHEMBL1004454 | 0.78 | KMT2A (0.51) | HSD11B1CDK4CCND1KMT2AMEN1 | |
| SCHEMBL6598473 | 0.78 | KMT2A (0.51) | TNFCDK4CCND1KMT2AMEN1 | |
| SCHEMBL1006489 | 0.78 | NAMPT (0.54) | CDK4CCND1KMT2AMEN1MLYCD | |
| SCHEMBL11210960 | 0.78 | HDAC6 (0.59) | CDK4CCND1KMT2AMEN1MLYCD | |
| SCHEMBL92123 | 0.77 | KMT2A (0.40) | TNFCDK4CCND1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1788429-B1 | Method of making a lithographic printing plate | AGFA GRAPHICS NV (BE) | 2009-03-18 | — | — | EP | disclosed |
| WO-2007057346-A2 | METHOD OF MAKING A LITHOGRAPHIC PRINTING PLATE | AGFA GRAPHICS NV (BE) | 2007-05-24 | — | — | WO | disclosed |
| EP-1788429-A1 | Method of making a lithographic printing plate | Agfa Graphics N.V. (BE) | 2007-05-23 | — | — | EP | disclosed |