SCHEMBL4362033

SCHEMBL4362033

O=C(c1ccccc1)N(CCS(=O)(=O)O)C(=O)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 3/20 0.43
ADRA2C P18825 1/20 0.40
HPGD P15428 2/20 0.40
ALDH1A1 P00352 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.39
KMT2A Q03164 2/20 0.38
CES1 P23141 2/20 0.38
LTA4H P09960 1/20 0.38
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 1/20 0.38
CYP3A4 P08684 1/20 0.38
MAPT P10636 1/20 0.38
ALOX15 P16050 1/20 0.38
MAPK1 P28482 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
DAO P14920 1/20 0.37
TSHR P16473 1/20 0.37
NAPRT Q6XQN6 1/20 0.37
CES2 O00748 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11418586 0.82 ADRA2C (0.47) HSD11B1ADRA2CLTA4H
SCHEMBL13901433 0.82 HSD11B1 (0.49) HSD11B1KMT2ALTA4HMEN1
SCHEMBL17685267 0.82 ADRA2C (0.48) ADRA2CHPGDALDH1A1L3MBTL1KMT2A
SCHEMBL11243472 0.79 LTA4H (0.39) KMT2ALTA4HALOX15
SCHEMBL1246672 0.76 HDAC3 (0.45) ADRA2CHPGDALDH1A1L3MBTL1KMT2A
SCHEMBL633271 0.75 ADRA2C (0.56) ADRA2CHPGDALDH1A1L3MBTL1KMT2A
SCHEMBL13571678 0.75 TP53 (0.52) ADRA2CHPGDALDH1A1KMT2ACES1
SCHEMBL13571480 0.72 HPGD (0.57) ADRA2CHPGDALDH1A1CES1CES2
SCHEMBL11575119 0.72 HDAC3 (0.53) ADRA2CHPGDALDH1A1L3MBTL1KMT2A
SCHEMBL16944257 0.71 ALDH1A1 (0.47) HSD11B1ADRA2CHPGDALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 656 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7615524-B2 Multicompartments containing laundering additives; fabric softener THE PROCTER & GAMBLE CO. (US) 2009-11-10 US disclosed
EP-1113071-B1 Detergent compositions PROCTER & GAMBLE (US) 2008-07-09 EP disclosed
US-20080113893-A1 Process for preparing detergent tablet ROWLAND BARRY 2008-05-15 US disclosed
US-7351683-B2 Laundry additive sachet THE PROCTER & GAMBLE COMPANY (US) 2008-04-01 US disclosed
EP-1165732-B1 FABRIC SOFTENING COMPONENT PROCTER & GAMBLE (US) 2008-02-13 EP disclosed
CN-100366715-C Detergent particle PROCTE & GAMBLE CO (US) 2008-02-06 CN disclosed
US-7320955-B2 Compositions comprising complexes of cyclodextrin and at least one laundry treatment active THE PROCTER & GAMBLE COMPANY (US) 2008-01-22 US disclosed
US-7304023-B2 Detergent product THE PROCTER & GAMBLE COMPANY (US) 2007-12-04 US disclosed
CN-100343378-C Non-aqueous detergent compositions contg. bleach PROCTER & GAMBLE (US) 2007-10-17 CN disclosed
EP-1255807-B1 DETERGENT PRODUCT PROCTER & GAMBLE (US) 2007-08-08 EP disclosed
WO-1995028466-A1 DETERGENTS CONTAINING A SURFACTANT AND A DELAYED RELEASE ENZYME THE PROCTER & GAMBLE COMPANY (US) 1995-10-26 WO disclosed
WO-1995028465-A1 DETERGENTS CONTAINING A BUILDER AND A DELAYED RELEASE PEROXYACID BLEACH SOURCE THE PROCTER & GAMBLE COMPANY (US) 1995-10-26 WO disclosed
WO-1995028464-A1 DETERGENTS CONTAINING A HEAVY METAL SEQUESTRANT AND A DELAYED RELEASE PEROXYACID BLEACH SYSTEM THE PROCTER & GAMBLE COMPANY (US) 1995-10-26 WO disclosed
WO-1995028468-A1 DETERGENT COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1995-10-26 WO disclosed
WO-1995028467-A1 DETERGENTS CONTAINING AN ENZYME AND A DELAYED RELEASE PEROXYACID BLEACHING SYSTEM THE PROCTER & GAMBLE COMPANY (US) 1995-10-26 WO disclosed
EP-0672749-A1 Bleaching compositions THE PROCTER & GAMBLE COMPANY (US) 1995-09-20 EP disclosed
WO-1995018206-A1 PEROXYACID BLEACH PRECURSOR PARTICLE COATED WITH A WATER SOLUBLE ORGANIC ACID IN PARTICULATE FORM THE PROCTER & GAMBLE COMPANY (US) 1995-07-06 WO disclosed
EP-0659876-A2 Detergent additive composition. THE PROCTER & GAMBLE COMPANY (US) 1995-06-28 EP disclosed
WO-1995012652-A1 DETERGENT COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1995-05-11 WO disclosed
WO-1995001416-A1 MACHINE DISHWASHING COMPOSITION CONTAINING OXYGEN BLEACH AND PARAFFIN OIL AND BENZOTRIAZOLE COMPOUND SILVER TARNISHING INHIBITORS THE PROCTER & GAMBLE COMPANY (US) 1995-01-12 WO disclosed