SCHEMBL13901982

SCHEMBL13901982

COC(=O)NCCCCC(NC(=O)OC)C(=O)NCCCCC(NC(=O)C(CCCCNC(=O)OC)NC(=O)OC)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ CPB1 P15086 1/20 0.46
▸ CPB2 Q96IY4 1/20 0.46
▸ FOLH1 Q04609 4/20 0.45
▸ SIRT1 Q96EB6 2/20 0.43
▸ SIRT6 Q8N6T7 1/20 0.43
▸ GLP1R P43220 8/20 0.43
▸ EPHX1 P07099 1/20 0.42
▸ TGM2 P21980 2/20 0.42
▸ NOD1 Q9Y239 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13026641 0.97 FOLH1 (0.47) CPB1CPB2FOLH1SIRT1GLP1R
SCHEMBL10017794 0.91 FOLH1 (0.51) FOLH1SIRT1EPHX1TGM2
SCHEMBL13057085 0.91 FOLH1 (0.51) FOLH1SIRT1EPHX1TGM2
SCHEMBL13498644 0.85 EPHX1 (0.53) SIRT1SIRT6GLP1REPHX1
SCHEMBL13498651 0.85 EPHX1 (0.62) SIRT1SIRT6GLP1REPHX1
SCHEMBL13498646 0.85 EPHX1 (0.57) SIRT1SIRT6GLP1REPHX1
SCHEMBL24431370 0.84 SIRT1 (0.53) CPB1CPB2SIRT1SIRT6EPHX1
SCHEMBL14262320 0.84 SIRT1 (0.44) CPB1CPB2SIRT1SIRT6GLP1R
SCHEMBL12192760 0.84 MEN1 (0.56) —
SCHEMBL13498562 0.83 SIRT1 (0.46) CPB1CPB2SIRT1SIRT6GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8703893-B2 Four branched dendrimer-PEG for conjugation to proteins and peptides CENTRO DE INGENIENIA GENETICA Y BIOTECNOLOGIA (CU) 2014-04-22 — — US disclosed
US-20090082537-A1 FOUR BRANCHED DENDRIMER-PEG FOR CONJUGATION TO PROTEINS AND PEPTIDES CENTRO DE INGENIENIA GENETICA Y BIOTECNOLOGIA (CU) 2009-03-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090082537-A1 FOUR BRANCHED DENDRIMER-PEG FOR CONJUGATION TO PROTEINS AND PEPTIDES HDGF, CLTB, EGFR CPB1 1690/4885CPB2 1669/4885FOLH1 786/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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