Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | SIRT1 | Q96EB6 | 11/20 | 0.51 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.51 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 11/20 | 0.41 |
| ▸ | SIRT3 | Q9NTG7 | 8/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | GLP1R | P43220 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13498651 | 0.94 | EPHX1 (0.62) | EPHX1SIRT1SIRT6CTSSCTSK | |
| SCHEMBL13498646 | 0.94 | EPHX1 (0.57) | EPHX1SIRT1SIRT6CTSSCTSK | |
| SCHEMBL24431370 | 0.87 | SIRT1 (0.53) | EPHX1SIRT1SIRT6SIRT2SIRT3 | |
| SCHEMBL14262320 | 0.87 | SIRT1 (0.44) | EPHX1SIRT1SIRT6CTSSCTSK | |
| SCHEMBL14805675 | 0.85 | SIRT1 (0.46) | EPHX1SIRT1SIRT6SIRT2SIRT3 | |
| SCHEMBL13901982 | 0.85 | CPB1 (0.46) | EPHX1SIRT1SIRT6GLP1R | |
| SCHEMBL17722384 | 0.85 | SIRT1 (0.46) | EPHX1SIRT1SIRT6CTSSCTSK | |
| SCHEMBL12410205 | 0.85 | SIRT1 (0.49) | SIRT1SIRT6SIRT2SIRT3 | |
| SCHEMBL13498562 | 0.85 | SIRT1 (0.46) | EPHX1SIRT1SIRT6CTSSCTSK | |
| SCHEMBL13661424 | 0.85 | EPHX1 (0.45) | EPHX1SIRT1SIRT6CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100035814-A1 | N-Terminal Pegylated Prolactin Receptor Molecules | NOVO NORDISK A/S (DK) | 2010-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100035814-A1 | N-Terminal Pegylated Prolactin Receptor Molecules | PRLHR, GHRHR, TRHR | EPHX1 4472/4885SIRT1 3828/4885SIRT6 2768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.